Year: 2020 | Month: October | Volume 10 | Issue 5
Clinical Study on Comparative Evaluation of Diagnostic Modalities in the Diagnosis of Hepatic Affections in Dogs
Pankaj Gupta
H.R. Bhardwaj
A.K. Gupta
D.K. Dwivedi
Ankur Sharma
Ashok Kumar
Dibyendu Chakraborty
DOI:10.30954/2277-940X.05.2020.7
Abstract:
A clinical study was conducted on 13 dogs including six apparently healthy dogs (Gp I) and seven dogs with symptoms of hepatobilliary involvement (Gp II) to evaluate different diagnostic modalities in making diagnosis. After recording signalment and history various hemato-biochemical parameters were estimated. Radiography and ultrasonography of liver was performed in all dogs. Thereafter, fine needle biopsy and histopathology were performed in Gp II dogs. The Hb and PCV were significantly low in Gp II as compared to Gp I whereas the TLC of Gp II was significantly higher than that of Gp I. The clotting time and bleeding time were significantly higher in Gp II as compared to Gp I. The ALT, AST and ALP values of Gp II were significantly higher than that of Gp I. The A:G ratio was significantly lower in Gp II as compared to that of Gp I. Sensitivity of radiography and ultrasonography were 57.14% and 100% and respectively. Accuracy of ultrasound guided biopsy was 100 % and different diseases diagnosed on histopathology were cholangiocellular carcinoma, liver cirrhosis, papillary adenocarcinoma, cystic adenocarcinoma, hemangiosarcoma and fibroadenoma. From the present study it was concluded that all the diagnostic modalities viz. laboratory tests, radiography and ultrasonography complimented each other in making diagnosis and predicting prognosis but the final diagnosis was obtained only with histopathology.
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